Sen. Lindsey Graham gets a 2026 challenge from Democrat Annie Andrews, who ran against Nancy Mace

Dr. Annie Andrews, the South Carolina Democrat who unsuccessfully challenged U.S. Rep. Nancy Mace in 2022, says she’s running against Republican U.S. Sen. Lindsey Graham in 2026, challenging the four-term incumbent in part due to what she characterized as his waffling positions over the course of his political career.

“He’s changed his position on nearly every issue over that time and that’s because, in my view, he doesn’t stand for anything or believe in anything other than what it takes to get reelected,” Andrews, a pediatrician in Charleston, told The Associated Press before a campaign rollout Thursday.

Andrews joins at least one other Democrat in a primary field.

In her launch video, Andrews says it’s “embarrassing” to see how politicians like Graham — at the moment one of President Donald Trump’s top Senate allies — have swung from criticizing Trump to working to gain his favor. The video features archival video of Graham bemoaning critics who called Trump a “kook” and then, a year earlier, using the same term to describe his former GOP primary foe in the 2016 presidential contest.

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